ADEVASCO

The Research Task entitled ‘Personalized endothelial diagnostics in anticancer treatment; towards modern vasculooncology’ [ADEVASCO (Aptamer-Based Diagnosis of Endothelium in Vasculooncology)] will be conducted by Jagellonian University in consortium with five Polish scientific units: Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences in Wrocław, Institute of Animal Reproduction and Food Research Polish Academy of Sciences in Olsztyn, Medical University of Gdańsk, Maria Sklodowska-Curie National Research Institute of Oncology in Gliwice and Warsaw University of Technology.

The goal of the ADEVASCO team’s scientific and research activities is to develop a new technology of the electrochemical aptasensor, based on aptamers and original methodological solutions based on polymer nanobrushes, mounted into a specially designed POCT apparatus with microfluidic system. This completely novel technology will provide a tool to solve the unmet medical need of an early companion diagnostics (CDx) for cardiovascular toxicities related to anticancer therapy.

The amount of funding allocated to the project is PLN 78,578,024.95

The Key Personnel of the Research Team consists of:

Prof Stefan Chłopicki, PhD – Research Team Leader / Jagellonian University

Prof Szczepan Zapotoczny, PhD / Jagellonian University

Prof Joanna Wietrzyk, PhD / Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences

Iwona Grabowska, PhD / Institute of Animal Reproduction and Food Research Polish Academy of Sciences

Prof Michał J. Markuszewski, PhD / Medical University of Gdańsk

Prof Ryszard T. Smoleński, PhD / Medical University of Gdańsk

Mateusz Tajstra, PhD / National Research Institute of Oncology

Prof Mariusz Pietrzak, PhD / Warsaw University of Technology